Product Research

Lightning™ & NeuroC3™

Lightning and NeuroC3 are both based on the same iconic formula of 36 vitamins, minerals, amino acids, and plant extracts that has been changing lives for over two decades. This unique formula has been the subject of 35+ medical journal publications covering various topics such as ADHD, anxiety, bipolar disorder, depression, mood lability, stress, and many more.

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Anxiety & Function

Research Snippet

Modified Brinley plots revealed decreases in anxiety and improvements in overall functioning for 10 out of 11 completing participants.

Bipolar Disorder

Research Snippet

Long-term remission was attained in all cases, defined as clinical stability with no discernible symptoms of bipolar disorder for at least one year.

ADHD & Mood

Research Snippet

Modified Brinley plots revealed a reduction, improved mood, and improved overall functioning during intervention phases, and deterioration during withdrawal.

Prosper

Prosper is our advanced direct-to-mouth gut health supplement. It uses the research-backed Bacillus Subtilis HU58® and Bacillus Coagulans SC208® strains which are delivered in spore form. This makes them tremendously resilient to the harsh conditions of the stomach while keeping the product shelf-stable. We also include prebiotics and digestive enzymes, making Prosper a complete gut-health solution.

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Healthy Microbiome

Our unique spore-form probiotic encourages the growth of other beneficial microbes12 as well as increases the production of beneficial short-chain fatty acids3.

Gut Health

Our two strains are proven to withstand the acidic environment of the stomach and reach the small intestine45 where they germinate to provide all their health benefits.

Immune System

HU58® may support a healthy immune system6710 by increasing the production of short-chain fatty acids8 which can promote anti-inflammatory effects9.

References:

  1. Marzorati M, Abbeele PVD, Bubeck SS, Bayne T, Krishnan K, Young A, Mehta D, DeSouza A. Bacillus subtilis HU58 and Bacillus coagulans SC208 Probiotics Reduced the Effects of Antibiotic-Induced Gut Microbiome Dysbiosis in An M-SHIME® Model. Microorganisms. 2020 Jul 11;8(7):1028. doi: 10.3390/microorganisms8071028. PMID: 32664604; PMCID: PMC7409217.
  2. Marzorati M, Van den Abbeele P, Bubeck S, Bayne T, Krishnan K, Young A. Treatment with a spore-based probiotic containing five strains of Bacillus induced changes in the metabolic activity and community composition of the gut microbiota in a SHIME® model of the human gastrointestinal system. Food Res Int. 2021 Nov;149:110676. doi: 10.1016/j.foodres.2021.110676. Epub 2021 Aug 30. PMID: 34600678.
  3. Cindy Duysburgh, Pieter Van den Abbeele, Kiran Krishnan, Thomas F. Bayne, Massimo Marzorati, A synbiotic concept containing spore-forming Bacillus strains and a prebiotic fiber blend consistently enhanced metabolic activity by modulation of the gut microbiome in vitro, International Journal of Pharmaceutics: X, Volume 1, 2019.
  4. Permpoonpattana, et al. Beneficial Microbes, June 2012; 3(2): 127-135
  5. Huynh A. Hong, et al. Research in Microbiology, Volume 160, Issue 6, 2009, Pages 375-379
  6. Huang JM, La Ragione RM, Nunez A, Cutting SM. Immunostimulatory activity of Bacillus spores. FEMS Immunol Med Microbiol. 2008 Jul;53(2):195-203.
  7. Simon M. Cutting, Ezio Ricca, Bacterial spore-formers: friends and foes, FEMS Microbiology Letters, Volume 358, Issue 2, September 2014, Pages 107–109.
  8. Bernardeau M, Lehtinen MJ, Forssten SD, Nurminen P. Importance of the gastrointestinal life cycle of Bacillus for probiotic functionality. J Food Sci Technol. 2017 Jul;54(8):2570-2584. doi: 10.1007/s13197-017-2688-3. Epub 2017 May 23. PMID: 28740315; PMCID: PMC5502041.
  9. Perez-Fons L, Steiger S, Khaneja R, Bramley PM, Cutting SM, Sandmann G, Fraser PD. Identification and the developmental formation of carotenoid pigments in the yellow/orange Bacillus spore-formers. Biochim Biophys Acta. 2011 Mar;1811(3):177-85. doi: 10.1016/j.bbalip.2010.12.009. Epub 2011 Jan 5. PMID: 21215325.
  10. Dound YA, Jadhav SS, Devale M, Tom Bayne, Kiran Krishnan, Mehta DS (2019) “The effect of Probiotic Bacillus subtilis HU58 on Immune function in Healthy Human”, The Indian Practitioner, 70(9), pp. 15-20.